Mankind has flourished ever since it escaped from the Dark Ages, ages where ignorance once ruled the fools, and superstitions were laws and norms. We start to think for ourselves. We start to reason about the nature, the environment, the celestial bodies. Regularities beget curiosity. Why is nature the way it is? A question whose answer will always approach the absolute truth, but never attain the truth. We live in a world of empiricism. We observe. We reason. That which explains in the clearest and simplest manner of the observations we made, are accorded the stature of facts. Facts, a body of assertions backed by assertions, and ultimately by axioms, are always never guaranteed to be the absolute truth. With this in mind, we question the validity of the methods by which we accrue facts. Can we not suppose that there is a highly advanced extra-terrestrial civilization, whose capabilities are so advanced it appears God-like, interfering with the very World and reality in which we live? For pure thought experiment, we put off our reservations aside, and recall the many cosmology observations of Galaxies and Clusters of them. They are measured to be moving faster than their mass could account for. Dark matters are presumed to be the missing factor. Many of the present generation of particle physicists devote their life to the search of dark matter. What if it never existed? What if other advanced civilizations were playing tricks on us? What if they set the laws of nature which we observe? What if world in which we reside was just mere creation? A purposeful creation? I do not, by this questioning, suggest the existence of God, for it is equally plausible to me that there exist a civilization so advanced it is able to create worlds, tweak laws of nature, and alter reality. What hope do we have of preventing such a thing? Before that, can we even hope to verify such a possibility of someone or something else sustaining or altering our reality? The brain-in-a-vat experiment should give us enough of an answer to this.